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Failure of lower motor neuron radial outgrowth precedes retrograde degeneration in a feline model of SMA
Feline SMA is a fully penetrant, autosomal recessive lower motor neuron disease in domestic cats that clinically resembles human SMA Type III. A whole genome linkage scan identified a ~140 kilobase deletion that abrogates expression of LIX1, a novel SMA candidate gene of unknown function. To charact...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355207/ https://ncbi.nlm.nih.gov/pubmed/22120001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23010 |
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