Pathogen-Induced Proapoptotic Phenotype and High CD95 (Fas) Expression Accompany a Suboptimal CD8(+) T-Cell Response: Reversal by Adenoviral Vaccine

MHC class Ia-restricted CD8(+) T cells are important mediators of the adaptive immune response against infections caused by intracellular microorganisms. Whereas antigen-specific effector CD8(+) T cells can clear infection caused by intracellular pathogens, in some circumstances, the immune response...

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Detalhes bibliográficos
Main Authors: Vasconcelos, José Ronnie, Bruña–Romero, Oscar, Araújo, Adriano F., Dominguez, Mariana R., Ersching, Jonatan, de Alencar, Bruna C. G., Machado, Alexandre V., Gazzinelli, Ricardo T., Bortoluci, Karina R., Amarante-Mendes, Gustavo P., Lopes, Marcela F., Rodrigues, Mauricio M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355083/
https://ncbi.nlm.nih.gov/pubmed/22615561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002699
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