Protein kinase A enhances lipopolysaccharide-induced IL-6, IL-8, and PGE(2 )production by human gingival fibroblasts

OBJECTIVE: Periodontal disease is accompanied by inflammation of the gingiva and destruction of periodontal tissues, leading to alveolar bone loss in severe clinical cases. Interleukin (IL)-6, IL-8, and the chemical mediator prostaglandin E(2 )(PGE(2)) are known to play important roles in inflammato...

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Main Authors: Ara, Toshiaki, Fujinami, Yoshiaki, Urano, Hiroko, Hirai, Kaname, Hatori, Toshimi, Miyazawa, Hiroo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355011/
https://ncbi.nlm.nih.gov/pubmed/22452847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-11-10
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