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The Intramolecular Diels–Alder Reaction of Tryptamine-Derived Zincke Aldehydes Is a Stepwise Process

Computational studies show that the base-mediated intramolecular Diels–Alder of tryptamine-derived Zincke aldehydes, used as a key step in the synthesis of the Strychnos alkaloids norfluorocurarine and strychnine, proceeds via a stepwise pathway. The experimentally determined importance of a potassi...

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Bibliografiske detaljer
Main Authors: Pham, Hung V., Martin, David B. C., Vanderwal, Christopher D., Houk, K. N.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354770/
https://ncbi.nlm.nih.gov/pubmed/22611483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SC01072K
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