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Podocyte GTPases regulate kidney filter dynamics

The way we are thinking about the kidney filtration barrier is changing from that of a static sieve into a highly dynamic structure regulated through the motility of podocyte foot processes. It has been shown in vitro that inactivation of the small GTPase RhoA causes hypermotility, whereas activatio...

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Bibliographic Details
Main Authors: Kistler, Andreas D., Altintas, Mehmet M., Reiser, Jochen
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354621/
https://ncbi.nlm.nih.gov/pubmed/22584591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.12
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