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ADF/cofilin proteins translocate to mitochondria during apoptosis but are not generally required for cell death signaling

Non-muscle cofilin (n-cofilin) is a member of the ADF/cofilin family of actin depolymerizing proteins. Recent studies reported a mitochondrial translocation of n-cofilin during apoptosis. As these studies also revealed impaired cytochrome c release and a block in apoptosis upon small interfering RNA...

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Detalhes bibliográficos
Main Authors: Rehklau, K, Gurniak, C B, Conrad, M, Friauf, E, Ott, M, Rust, M B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354050/
https://ncbi.nlm.nih.gov/pubmed/22139132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.180
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