Llwytho...

Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells

EZH2/H3K27me3 and polycomb group complex (PcG) play a major role in regulating global gene expression including tumor suppressor genes. EZH2 is linked to cell cycle regulated EZH2 phosphorylation by CDK1, a mitotic kinase which increases in arrested mitosis compared to S phase. CDK1 phosphorylation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: French, BA, Oliva, J, Bardag-Gorce, F, Li, J, Zhong, J, Bulson, V, French, SW
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354044/
https://ncbi.nlm.nih.gov/pubmed/22465358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.02.003
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