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Multiple Interferon Stimulated Genes Synergize with the Zinc Finger Antiviral Protein to Mediate Anti-Alphavirus Activity

The zinc finger antiviral protein (ZAP) is a host factor that mediates inhibition of viruses in the Filoviridae, Retroviridae and Togaviridae families. We previously demonstrated that ZAP blocks replication of Sindbis virus (SINV), the prototype Alphavirus in the Togaviridae family at an early step...

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Detalhes bibliográficos
Main Authors: Karki, Sophiya, Li, Melody M. H., Schoggins, John W., Tian, Suyan, Rice, Charles M., MacDonald, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353916/
https://ncbi.nlm.nih.gov/pubmed/22615998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037398
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