Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment

BACKGROUND: Prolactin is secreted from the pituitary gland and other organs, as well as by cells such as lymphocytes. Prolactin has an immunostimulatory effect and is associated with autoimmune diseases that are characterised by abnormal B cell activation, such as systemic lupus erythematosus (SLE)....

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Main Authors: Ledesma-Soto, Yadira, Blanco-Favela, Francisco, Fuentes-Pananá, Ezequiel M, Tesoro-Cruz, Emiliano, Hernández-González, Rafael, Arriaga-Pizano, Lourdes, Legorreta-Haquet, María V, Montoya-Diaz, Eduardo, Chávez-Sánchez, Luis, Castro-Mussot, María E, Chávez-Rueda, Adriana K
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353839/
https://ncbi.nlm.nih.gov/pubmed/22404893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-13-11
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