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Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney
Thiazolidinediones (TZDs), known as peroxisome proliferator-activated receptor (PPAR) agonists, are used to treat type 2 diabetes. However, ∼5% of patients experience the treatment-limiting side effect of edema. Studies have implicated activation of the epithelial sodium channel (ENaC) as a cause of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353644/ https://ncbi.nlm.nih.gov/pubmed/22169011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00306.2011 |
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