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Ensemble Modeling of Cancer Metabolism

The metabolic behavior of cancer cells is adapted to meet their proliferative needs, with notable changes such as enhanced lactate secretion and glucose uptake rates. In this work, we use the Ensemble Modeling (EM) framework to gain insight and predict potential drug targets for tumor cells. EM gene...

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Detalhes bibliográficos
Main Authors: Khazaei, Tahmineh, McGuigan, Alison, Mahadevan, Radhakrishnan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353412/
https://ncbi.nlm.nih.gov/pubmed/22623918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00135
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