Matrix metalloproteinase-9 contributes to parenchymal hemorrhage and necrosis in the remnant liver after extended hepatectomy in mice

AIM: To investigate the effect of matrix metalloproteinase-9 (MMP-9) on the remnant liver after massive hepatectomy in the mouse. METHODS: Age-matched, C57BL/6 wild-type (WT), MMP-9(-/-), and tissue inhibitors of metalloproteinases (TIMP)-1(-/-) mice were used. The mice received 80%-partial hepatect...

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Autors principals: Ohashi, Norifumi, Hori, Tomohide, Chen, Florence, Jermanus, Sura, Eckman, Christopher B, Nakao, Akimasa, Uemoto, Shinji, Nguyen, Justin H
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353366/
https://ncbi.nlm.nih.gov/pubmed/22654423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i19.2320
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