Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial

BACKGROUND: Colorectal cancer is one of the major neoplasms and a leading cause of cancer death worldwide, and new preventive strategies are needed to lower the burden of this disease. Metformin, a biguanide, which is widely used for treating diabetes mellitus, has recently been suggestive to have a...

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Detalhes bibliográficos
Main Authors: Higurashi, Takuma, Takahashi, Hirokazu, Endo, Hiroki, Hosono, Kunihiro, Yamada, Eiji, Ohkubo, Hidenori, Sakai, Eiji, Uchiyama, Takashi, Hata, Yasuo, Fujisawa, Nobutaka, Uchiyama, Shiori, Ezuka, Akiko, Nagase, Hajime, Kessoku, Takaomi, Matsuhashi, Nobuyuki, Yamanaka, Shoji, Inayama, Yoshiaki, Morita, Satoshi, Nakajima, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353167/
https://ncbi.nlm.nih.gov/pubmed/22443173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-118
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