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RhoA: A therapeutic target for chronic myeloid leukemia

BACKGROUND: Chronic Myeloid Leukemia (CML) is a malignant pluripotent stem cells disorder of myeloid cells. In CML patients, polymorphonuclear leukocytes (PMNL) the terminally differentiated cells of myeloid series exhibit defects in several actin dependent functions such as adhesion, motility, chem...

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Detalhes bibliográficos
Main Authors: Molli, Poonam R, Pradhan, Madhura B, Advani, Suresh H, Naik, Nishigandha R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353160/
https://ncbi.nlm.nih.gov/pubmed/22443473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-16
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