تحميل...
Sequence-Specific Recognition of Cancer Drug-DNA Adducts by HMGB1a Repair Protein
The efficacy of cancer drugs such as cisplatin (Cp) and oxaliplatin (Ox), which covalently bind to DNA to form drug-DNA adducts, is linked to their recognition by repair proteins such as HMGB1a. Previous experimental studies showed that HMGB1a's binding affinity for Cp- and Ox-DNA varies with t...
محفوظ في:
| المؤلفون الرئيسيون: | , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
The Biophysical Society
2012
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353062/ https://ncbi.nlm.nih.gov/pubmed/22677386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.013 |
| الوسوم: |
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