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The Power of Hard-Sphere Models: Explaining Side-Chain Dihedral Angle Distributions of Thr and Val

The energy functions used to predict protein structures typically include both molecular-mechanics and knowledge-based terms. In contrast, our approach is to develop robust physics- and geometry-based methods. Here, we investigate to what extent simple hard-sphere models can be used to predict side-...

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Библиографические подробности
Главные авторы: Zhou, Alice Qinhua, O'Hern, Corey S., Regan, Lynne
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353012/
https://ncbi.nlm.nih.gov/pubmed/22677388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.061
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