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Shotgun lipidomics analysis of 4-hydroxyalkenal species directly from lipid extracts after one-step in situ derivatization

4-Hydroxyalkenal species are a class of peroxidative products of polyunsaturated fatty acids, which serve as “toxic second messengers” in cellular systems. Investigation of their cellular role is hindered due to the lack of sensitive, reliable, robust method for identification and quantification of...

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Autori principali: Wang, Miao, Fang, Huafeng, Han, Xianlin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352972/
https://ncbi.nlm.nih.gov/pubmed/22500579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac300695p
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