GVHD-Related, Cytokine-Driven Apoptosis Depends on p73 in Cytokeratin 15-Positive Target Cells

Acute graft-versus-host disease (GVHD), a major complication of allogeneic stem cell transplantation, involves cytotoxic soluble and cellular effectors that induce apoptosis selectively in normally apoptosis-resistant, cytokeratin 15 (K15)-expressing epithelial stem cells that reside at tips of rete...

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Hlavní autoři: Zhan, Qian, Korngold, Robert, Lezcano, Cecilia, McKeon, Frank, Murphy, George F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352968/
https://ncbi.nlm.nih.gov/pubmed/22469882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2012.02.004
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