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Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell–cell fusion

Osteoclasts fuse to form multinucleated cells during osteoclastogenesis. This process is mediated by dynamic rearrangement of the plasma membrane and cytoskeleton, and it requires numerous factors, many of which have been identified. The underlying mechanism remains obscure, however. In this paper,...

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Detalhes bibliográficos
Main Authors: Oikawa, Tsukasa, Oyama, Masaaki, Kozuka-Hata, Hiroko, Uehara, Shunsuke, Udagawa, Nobuyuki, Saya, Hideyuki, Matsuo, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352951/
https://ncbi.nlm.nih.gov/pubmed/22584907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111116
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