Synaptic Activity Unmasks Dopamine D2 Receptor Modulation of a Specific Class of Layer V Pyramidal Neurons in Prefrontal Cortex

Dopamine D2 receptors (D2Rs) play a major role in the function of the prefrontal cortex (PFC), and may contribute to prefrontal dysfunction in conditions such as schizophrenia. Here we report that in mouse PFC, D2Rs are selectively expressed by a subtype of layer V pyramidal neurons that have thick...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gee, Steven, Ellwood, Ian, Patel, Tosha, Luongo, Francisco, Deisseroth, Karl, Sohal, Vikaas S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2012
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352768/
https://ncbi.nlm.nih.gov/pubmed/22492051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5835-11.2012
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