Synaptic Activity Unmasks Dopamine D2 Receptor Modulation of a Specific Class of Layer V Pyramidal Neurons in Prefrontal Cortex

Dopamine D2 receptors (D2Rs) play a major role in the function of the prefrontal cortex (PFC), and may contribute to prefrontal dysfunction in conditions such as schizophrenia. Here we report that in mouse PFC, D2Rs are selectively expressed by a subtype of layer V pyramidal neurons that have thick...

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Bibliographic Details
Main Authors: Gee, Steven, Ellwood, Ian, Patel, Tosha, Luongo, Francisco, Deisseroth, Karl, Sohal, Vikaas S.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352768/
https://ncbi.nlm.nih.gov/pubmed/22492051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5835-11.2012
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