Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence

Neisseria meningitidis can utilize haem, haemoglobin and haemoglobin–haptoglobin complexes as sources of iron via two TonB-dependent phase variable haemoglobin receptors, HmbR and HpuAB. HmbR is over-represented in disease isolates, suggesting a link between haemoglobin acquisition and meningococcal...

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Main Authors: Tauseef, Isfahan, Harrison, Odile B., Wooldridge, Karl G., Feavers, Ian M., Neal, Keith R., Gray, Stephen J., Kriz, Paula, Turner, David P. J., Ala’Aldeen, Dlawer A. A., Maiden, Martin C. J., Bayliss, Christopher D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for General Microbiology 2011
Ábhair:
Microbial Pathogenicity
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352162/
https://ncbi.nlm.nih.gov/pubmed/21310784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.046946-0
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