Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Passive transfer of broadly neutralizing HIV antibodies can prevent infection, which suggests that vaccines that elicit such antibodies would be protective. Thus far, however, few broadly neutralizing HIV antibodies that occur naturally have been characterized. To determine whether these antibodies...

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Detalhes bibliográficos
Main Authors: Scheid, Johannes F., Mouquet, Hugo, Ueberheide, Beatrix, Diskin, Ron, Klein, Florian, Oliveira, Thiago Y. K., Pietzsch, John, Fenyo, David, Abadir, Alexander, Velinzon, Klara, Hurley, Arlene, Myung, Sunnie, Boulad, Farid, Poignard, Pascal, Burton, Dennis R., Pereyra, Florencia, Ho, David D., Walker, Bruce D., Seaman, Michael S., Bjorkman, Pamela J., Chait, Brian T., Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351836/
https://ncbi.nlm.nih.gov/pubmed/21764753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1207227
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