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Mutual Remodeling and Conformation Grid: a Mediator Code?
How does a common RNA polymerase II apparatus generate a complex pattern of transcripts in response to many gene-specific transcription factors and in accordance with cell’s state? Cai et al. (2012) reveal that the process involves coordinated conformational changes in Pol II and Mediator.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351759/ https://ncbi.nlm.nih.gov/pubmed/22579244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.04.008 |
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