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Molecular pathogenesis and targeted therapeutics in Ewing sarcoma/primitive neuroectodermal tumours

BACKGROUND: Ewing sarcoma/PNET is managed with treatment paradigms involving combinations of chemotherapy, surgery, and sometimes radiation. Although the 5-year survival rate of non-metastatic disease approaches 70%, those cases that are metastatic and those that recur have 5-year survival rates of...

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Bibliographic Details
Main Authors: Kelleher, Fergal C, Thomas, David M
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351706/
https://ncbi.nlm.nih.gov/pubmed/22587874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-2-6
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