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In Vivo Detection of (13)C Isotopomer Turnover in the Human Brain by Sequential Infusion of (13)C Labeled Substrates

This study demonstrates the feasibility of simultaneously detecting human brain metabolites labeled by two substrates infused in a sequential order. In vivo (13)C spectra of carboxylic/amide carbons were acquired only during the infusion of the second substrate. This approach allowed dynamic detecti...

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Autori principali: Li, Shizhe, Zhang, Yan, Araneta, Maria Ferraris, Xiang, Yun, Johnson, Christopher, Innis, Robert, Shen, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351698/
https://ncbi.nlm.nih.gov/pubmed/22578550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmr.2012.03.012
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