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Engineering a Polymeric Gene Delivery Vector Based on Poly(ethylenimine) and Hyaluronic Acid
In this work, the effects of primary amines, ligand targeting, and overall charge on the effectiveness of branched poly(ethylenimine)-hyaluronic acid conjugate (bPEI-HA) zwitterionic gene delivery vectors are investigated. To elucidate the relative importance of each of these parameters, the zeta po...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351541/ https://ncbi.nlm.nih.gov/pubmed/22455481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300145q |
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