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Inner workings and regulatory inputs that control Polycomb repressive complex 2
Polycomb repressive complex 2 (PRC2) is a conserved multisubunit enzyme that methylates histone H3 on lysine-27. This chromatin modification is a hallmark of target genes transcriptionally silenced by the Polycomb system. At its core, PRC2 activity depends upon the SET domain active site of its cata...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351537/ https://ncbi.nlm.nih.gov/pubmed/22349693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-012-0361-1 |
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