Innate Immune Response of Human Plasmacytoid Dendritic Cells to Poxvirus Infection Is Subverted by Vaccinia E3 via Its Z-DNA/RNA Binding Domain

Plasmacytoid dendritic cells (pDCs) play important roles in antiviral innate immunity by producing type I interferon (IFN). In this study, we assess the immune responses of primary human pDCs to two poxviruses, vaccinia and myxoma virus. Vaccinia, an orthopoxvirus, was used for immunization against...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Cao, Hua, Dai, Peihong, Wang, Weiyi, Li, Hao, Yuan, Jianda, Wang, Fangjin, Fang, Chee-Mun, Pitha, Paula M, Liu, Jia, Condit, Richard C, McFadden, Grant, Merghoub, Taha, Houghton, Alan N, Young, James W, Shuman, Stewart, Deng, Liang
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351467/
https://ncbi.nlm.nih.gov/pubmed/22606294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036823
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires