A Novel sLRP6E1E2 Inhibits Canonical Wnt Signaling, Epithelial-to-Mesenchymal Transition, and Induces Mitochondria-Dependent Apoptosis in Lung Cancer

Aberrant activation of the Wnt pathway contributes to human cancer progression. Antagonists that interfere with Wnt ligand/receptor interactions can be useful in cancer treatments. In this study, we evaluated the therapeutic potential of a soluble Wnt receptor decoy in cancer gene therapy. We design...

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Autores principales: Lee, Jung-Sun, Hur, Man-Wook, Lee, Seong Kyung, Choi, Won-Il, Kwon, Young-Guen, Yun, Chae-Ok
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351461/
https://ncbi.nlm.nih.gov/pubmed/22606268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036520
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