Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs

PURPOSE: To define gene expression changes associated with diabetic retinopathy in a mouse model using next generation sequencing, and to utilize transcriptome signatures to assess molecular pathways by which pharmacological agents inhibit diabetic retinopathy. METHODS: We applied a high throughput...

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Главные авторы: Kandpal, Raj P., Rajasimha, Harsha K., Brooks, Matthew J., Nellissery, Jacob, Wan, Jun, Qian, Jiang, Kern, Timothy S., Swaroop, Anand
Формат: Artigo
Язык:Inglês
Опубликовано: Molecular Vision 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351417/
https://ncbi.nlm.nih.gov/pubmed/22605924
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