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Restoration of a translational stop-start overlap reinstates translational coupling in a mutant trpB'-trpA gene pair of the Escherichia coli tryptophan operon.

The trpB and trpA coding regions of the polycistronic trp mRNA of Escherichia coli are separated by overlapping translation stop and start codons. Efficient translation of the trpA coding region is subject to translational coupling, i.e., maximal trpA expression is dependent on prior translation of...

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Publicat a:Nucleic Acids Res
Autors principals: Das, A, Yanofsky, C
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1989
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335135/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2685759/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.22.9333
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