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Targeted Taste Cell-specific Overexpression of Brain-derived Neurotrophic Factor in Adult Taste Buds Elevates Phosphorylated TrkB Protein Levels in Taste Cells, Increases Taste Bud Size, and Promotes Gustatory Innervation

Brain-derived neurotrophic factor (BDNF) is the most potent neurotrophic factor in the peripheral taste system during embryonic development. It is also expressed in adult taste buds. There is a lack of understanding of the role of BDNF in the adult taste system. To address this, we generated novel t...

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Detalhes bibliográficos
Main Authors: Nosrat, Irina V., Margolskee, Robert F., Nosrat, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351349/
https://ncbi.nlm.nih.gov/pubmed/22442142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.328476
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