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Expanding the Role of 3-O Sulfated Heparan Sulfate in Herpes Simplex Virus Type-1 Entry

Heparan sulfate (HS) proteoglycans are commonly exploited by multiple viruses for initial attachment to host cells. Herpes simplex virus-1 (HSV-1) is unique because it can use HS for both attachment and penetration, provided specific binding sites for HSV-1 envelope glycoprotein gD are present. The...

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Bibliographic Details
Main Authors: O’Donnell, Christopher D., Kovacs, Maria, Akhtar, Jihan, Valyi-Nagy, Tibor, Shukla, Deepak
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351100/
https://ncbi.nlm.nih.gov/pubmed/20004926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.11.011
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