Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer

BACKGROUND: Cancers often arise within an area of cells (e.g. an epithelial patch) that is predisposed to the development of cancer, i.e. a "field of cancerization" or "field defect." Sporadic colon cancer is characterized by an elevated mutation rate and genomic instability. If...

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Detalhes bibliográficos
Main Authors: Facista, Alexander, Nguyen, Huy, Lewis, Cristy, Prasad, Anil R, Ramsey, Lois, Zaitlin, Beryl, Nfonsam, Valentine, Krouse, Robert S, Bernstein, Harris, Payne, Claire M, Stern, Stephen, Oatman, Nicole, Banerjee, Bhaskar, Bernstein, Carol
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351028/
https://ncbi.nlm.nih.gov/pubmed/22494821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-3-3
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