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Bone-seeking TRAP conjugates: surprising observations and their implications on the development of gallium-68-labeled bisphosphonates

BACKGROUND: Bisphosphonates possess strong affinity to bone. (99m)Tc bisphosphonate complexes are widely used for bone scintigraphy. For positron emission tomography (PET) bone imaging, Ga-68-based PET tracers based on bisphosphonates are highly desirable. FINDINGS: Two trimeric bisphosphonate conju...

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Autors principals: Notni, Johannes, Plutnar, Jan, Wester, Hans-Jürgen
Format: Artigo
Idioma:Inglês
Publicat: Springer 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351026/
https://ncbi.nlm.nih.gov/pubmed/22464278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-2-13
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