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Mechanisms behind Functional Avidity Maturation in T Cells
During an immune response antigen-primed B-cells increase their antigen responsiveness by affinity maturation mediated by somatic hypermutation of the genes encoding the antigen-specific B-cell receptor (BCR) and by selection of higher-affinity B cell clones. Unlike the BCR, the T-cell receptor (TCR...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351025/ https://ncbi.nlm.nih.gov/pubmed/22611418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/163453 |
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