Distinct transcriptional outputs associated with mono- and di-methylated histone H3 arginine 2

Dimethylation of histone H3 arginine 2 (H3R2me2) maintains transcriptional silencing by inhibiting Set-1 mediated trimethylation of H3K4. Here we demonstrate that arginine 2 is also monomethylated (H3R2me1) in yeast but that its functional characteristics are distinct from H3R2me2: (a) H3R2me1 does...

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Bibliographic Details
Main Authors: Kirmizis, Antonis, Santos-Rosa, Helena, Penkett, Christopher J., Singer, Michael A., Green, Roland D., Kouzarides, Tony
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350867/
https://ncbi.nlm.nih.gov/pubmed/19270702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1569
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