Characterization of Bone Resorption in Novel In Vitro and In Vivo Models of Oral Squamous Cell Carcinoma

OBJECTIVES: Oral squamous cell carcinoma (OSCC) is the most commonly diagnosed oral malignancy in humans and cats and frequently invades bone. The objective of this study was to determine if feline OSCC serves as a relevant model of human OSCC in terms of osteolytic behavior and expression of bone r...

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Main Authors: Martin, Chelsea K., Dirksen, Wessel P., Shu, Sherry T., Werbeck, Jillian L., Thudi, Nanda K., Yamaguchi, Mamoru, Wolfe, Tobie D., Heller, Kristin N., Rosol, Thomas J.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350825/
https://ncbi.nlm.nih.gov/pubmed/22265717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2011.12.012
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https://ncbi.nlm.nih.gov/pmc/articles/PMC3350825/
https://ncbi.nlm.nih.gov/pubmed/22265717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2011.12.012