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Mec1p associates with functionally compromised telomeres

In many organisms, telomere DNA consists of simple sequence repeat tracts that are required to protect the chromosome end. In the yeast Saccharomyces cerevisiae, tract maintenance requires two checkpoint kinases of the ATM family, Tel1p and Mec1p. Previous work has shown that Tel1p is recruited to f...

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Autors principals: Hector, Ronald E., Ray, Alo, Chen, Bo-Ruei, Shtofman, Rebecca, Berkner, Kathleen L., Runge, Kurt W.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350766/
https://ncbi.nlm.nih.gov/pubmed/22289863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-011-0359-0
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