Assessing the Relevance of in vitro Studies in Nanotoxicology by Examining Correlations between in vitro and in vivo Data

There is an urgent need for in vitro screening assays to evaluate nanoparticle (NP) toxicity. However, the relevance of in vitro assays is still disputable. We administered doses of TiO(2) NPs of different sizes to alveolar epithelial cells in vitro and the same NPs by intratracheal instillation in...

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Main Authors: Han, Xianglu, Corson, Nancy, Wade-Mercer, Pamela, Gelein, Robert, Jiang, Jingkun, Sahu, Manoranjan, Biswas, Pratim, Finkelstein, Jacob N., Elder, Alison, Oberdörster, Günter
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350601/
https://ncbi.nlm.nih.gov/pubmed/22487507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2012.03.006
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