Haploinsufficiency of the E3 Ubiquitin Ligase C-Terminus of Heat Shock Cognate 70 Interacting Protein (CHIP) Produces Specific Behavioral Impairments

The multifunctional E3 ubiquitin ligase CHIP is an essential interacting partner of HSP70, which together promote the proteasomal degradation of client proteins. Acute CHIP overexpression provides neuroprotection against neurotoxic mitochondrial stress, glucocorticoids, and accumulation of toxic amy...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: McLaughlin, BethAnn, Buendia, Matthew A., Saborido, Tommy P., Palubinsky, Amy M., Stankowski, Jeannette N., Stanwood, Gregg D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350526/
https://ncbi.nlm.nih.gov/pubmed/22606257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036340
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados