The Effect of Ketoconazole on Post-Burn Inflammation, Hypermetabolism and Clinical Outcomes

BACKGROUND: Hypercortisolemia has been suggested as a primary hormonal mediator of whole-body catabolism following severe burn injury. Ketoconazole, an anti-fungal agent, inhibits cortisol synthesis. We, therefore, studied the effect of ketoconazole on post-burn cortisol levels and the hyper-catabol...

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Bibliografiska uppgifter
Huvudupphovsmän: Jeschke, Marc G., Williams, Felicia N., Finnerty, Celeste C., Rodriguez, Noe A., Kulp, Gabriela A., Ferrando, Arny, Norbury, William B., Suman, Oscar E., Kraft, Robert, Branski, Ludwik K., Al-mousawi, Ahmed M., Herndon, David N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350497/
https://ncbi.nlm.nih.gov/pubmed/22606232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035465
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