Two remote glucocorticoid responsive units interact cooperatively to promote glucocorticoid induction of rat tyrosine aminotransferase gene expression.

Tyrosine aminotransferase (TAT) gene transcription is specifically activated by glucocorticoid hormones in liver cells. This regulation involves a glucocorticoid responsive region located 2,500 bases upstream from the transcription start site of the rate gene. By transient transfection of TAT-CAT fu...

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Hauptverfasser: Grange, T, Roux, J, Rigaud, G, Pictet, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC335037/
https://ncbi.nlm.nih.gov/pubmed/2573877
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