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Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields

The mechanisms mediating hematopoietic stem and progenitor cell (HSPC) mobilization by G-CSF are complex. We have found previously that G-CSF–enforced mobilization is controlled by peripheral sympathetic nerves via norepinephrine (NE) signaling. In the present study, we show that G-CSF likely alters...

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Bibliografische gegevens
Hoofdauteurs: Lucas, Daniel, Bruns, Ingmar, Battista, Michela, Mendez-Ferrer, Simon, Magnon, Claire, Kunisaki, Yuya, Frenette, Paul S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350363/
https://ncbi.nlm.nih.gov/pubmed/22422821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-07-367102
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