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A Dirichlet Process Prior for Estimating Lineage-Specific Substitution Rates

We introduce a new model for relaxing the assumption of a strict molecular clock for use as a prior in Bayesian methods for divergence time estimation. Lineage-specific rates of substitution are modeled using a Dirichlet process prior (DPP), a type of stochastic process that assumes lineages of a ph...

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Autors principals: Heath, Tracy A., Holder, Mark T., Huelsenbeck, John P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350323/
https://ncbi.nlm.nih.gov/pubmed/22049064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msr255
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