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Corticosterone pretreatment suppresses stress-induced hypothalamic-pituitary-adrenal axis activity via multiple actions that vary with time, site of action and de novo protein synthesis

Glucocorticoid regulation of the hypothalamic-pituitary-adrenal (HPA) axis is believed to depend on multiple actions operative within discrete time domains. However, the underlying cellular and molecular mechanism for those glucocorticoid actions remain undetermined. Moreover, there is an absence of...

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Bibliographic Details
Main Authors: Osterlund, Chad, Spencer, Robert L.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350321/
https://ncbi.nlm.nih.gov/pubmed/21205835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-10-0413
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