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The different competitive abilities of viral TAATGARAT elements and cellular octamer motifs, mediate the induction of viral immediate-early genes and the repression of the histone H2B gene in herpes simplex virus infected cells.

An HSV virion component, Vmw65, interacts with cellular transcription factors to transactivate TAATGARAT-containing viral genes and some cellular genes containing the related octamer element. We show that the octamer-containing histone H2B promoter can be trans-activated by transfection of Vmw65 but...

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Main Authors: Latchman, D S, Partidge, J F, Estridge, J K, Kemp, L M
格式: Artigo
語言:Inglês
出版: 1989
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC335025/
https://ncbi.nlm.nih.gov/pubmed/2555775
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