Epithelial-mesenchyme transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1

Pro-inflammatory cytokines produced in the tumor microenvironment facilitate tumor development and metastatic progression. In particular, TNF-α promotes cancer invasion and angiogenesis associated with epithelial-mesenchyme transition (EMT), however, the mechanisms underlying its induction of EMT in...

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Autors principals: Li, Chia-Wei, Xia, Weiya, Huo, Longfei, Lim, Seung-Oe, Wu, Yun, Hsu, Jennifer L., Chao, Chi-Hong, Yamaguchi, Hirohito, Yang, Neng-Kai, Ding, Qingqing, Wang, Yan, Lai, Yun-Ju, LaBaff, Adam M., Wu, Ting-Jung, Lin, Been-Ren, Yang, Muh-Hwa, Hortobagyi, Gabriel N., Hung, Mien-Chie
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350107/
https://ncbi.nlm.nih.gov/pubmed/22253230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3123
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