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On the genome-wide analysis of copy number variants in family-based designs: Methods for combining family-based and population based information for testing dichotomous or quantitative traits, or completely ascertained samples

We propose a new approach for the analysis of copy number variants (CNVs)for genome-wide association studies in family-based designs. Our new overall association test combines the between-family component and the within-family component of the data so that the new test statistic is fully efficient a...

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Bibliografiske detaljer
Main Authors: Murphy, Amy, Won, Sungho, Rogers, Angela, Chu, Jen-Hwa, Raby, Benjamin A, Lange, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349936/
https://ncbi.nlm.nih.gov/pubmed/20718041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20515
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