PTEN Regulates PDGF Ligand Switch for β-PDGFR Signaling in Prostate Cancer

Platelet-derived growth factor (PDGF) family members are potent growth factors that regulate cell proliferation, migration, and transformation. Clinical studies have shown that both PDGF receptor β (β-PDGFR) and its ligand PDGF D are up-regulated in primary prostate cancers and bone metastases, wher...

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Detalles Bibliográficos
Autores principales: Conley-LaComb, M. Katie, Huang, Wei, Wang, Shihua, Shi, Dongping, Jung, Young Suk, Najy, Abdo, Fridman, Rafael, Bonfil, R. Daniel, Cher, Michael L., Chen, Yong Q., Kim, Hyeong-Reh Choi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2012
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349886/
https://ncbi.nlm.nih.gov/pubmed/22209699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.11.021
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